Laboratory research only. Never for use in people or animals. Qualified research customers only.
Select current lots report over 99% purity Exact results vary by material and lot. View lab records →
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Form MOTS-C research material vial
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Muscle & Performance Available for research

Lot-documented reference material

MOTS-C

A synthetic peptide reference material backed by lot-specific identity and purity reporting.

99.53% Reported purityCurrent lot DPS-7058391 · UPLC + mass spectrometry View lot report →
$85 CoA available
One-time research orderNo subscription
10 mg
1
See lab records

Free U.S. shipping · Freeze-dried · CoA available

Independent lot recordLot DPS-7058391 · 99.53% purity · UPLC / mass spectrometryOpen lot report →
Lab-reported identityUPLC & mass spectrometry
Lot matchedCoA available
Freeze-driedReference material
Research onlyQualified buyers
01Material details

Review the identity, current reported result, methods, storage note, and document status in the material table below.

02Independent record

Open the independent report above to verify the values published on this page before placing a research order.

03Research-use requirements

For laboratory research only. Never for use in people or animals. Obtain and review the supplier-issued SDS before handling or storage.

04Potential human benefits
  • Metabolic flexibilityMOTS-C activates stress-adaptation pathways including AMPK, helping cells shift fuel use when energy demand rises. That mechanism is compelling for insulin-resistance and metabolic-health research.
  • Glucose regulationPreclinical work links MOTS-C signaling to improved glucose handling and insulin sensitivity, while human studies show that circulating MOTS-C responds to exercise and metabolic stress.
  • Physical capacity + healthy agingIn older mice, administered MOTS-C improved strength, gait, and exercise capacity. Human benefit has not yet been demonstrated, but the exercise-linked biology makes it a high-interest longevity target.

See what human studies have shown and what remains unknown.

The Form standard

Built to be examined,
not assumed.

Every listing keeps the material, current record, and research boundary in one clear review path.

01Lot-linked record

The available report is connected directly to the listing.

02Methods shown

Review the stated analytical methods before ordering.

03Freeze-dried format

Presented as a laboratory reference material.

04Clear limits

Research only. Never for use in people or animals.

Potential human relevance

A mitochondrial signal
that behaves like exercise.

MOTS-C is encoded within mitochondrial DNA and helps cells respond to energetic stress. Human studies show that exercise raises naturally occurring MOTS-C in muscle and circulation, while animal studies suggest administered MOTS-C can improve metabolic flexibility, physical capacity, and age-related decline.

01

Metabolic flexibility

MOTS-C activates stress-adaptation pathways including AMPK, helping cells shift fuel use when energy demand rises. That mechanism is compelling for insulin-resistance and metabolic-health research.

02

Glucose regulation

Preclinical work links MOTS-C signaling to improved glucose handling and insulin sensitivity, while human studies show that circulating MOTS-C responds to exercise and metabolic stress.

03

Physical capacity + healthy aging

In older mice, administered MOTS-C improved strength, gait, and exercise capacity. Human benefit has not yet been demonstrated, but the exercise-linked biology makes it a high-interest longevity target.

How the potential connects to the biology

01 / Mechanism

Why it may matter

Mitochondrial-to-nuclear stress signaling and metabolic adaptation pathways.

02 / Research markers

What studies track

Gene expression, oxygen consumption, AMPK-linked signaling, substrate use, and cellular stress response.

03 / Evidence level

How strong is the evidence?

Human exercise-response evidence for endogenous MOTS-C; administered-peptide benefits remain preclinical.

What remains unknown: Humans in the cited work produced endogenous MOTS-C in response to exercise; they were not treated with MOTS-C. Performance and healthy-aging benefits remain preclinical hypotheses.

Primary study: MOTS-C, exercise, and aging models Human study: exercise and circulating mitochondrial peptides

Material details

The essentials.

The current lot report lists the material identity, purity result, and test methods in one place.

CAS number1627580-64-6
Molecular formulaC101H152N28O22S2
Molecular weightApproximately 2174.64 g/mol
Lot result99.53% purity; white lyophilized powder
Tested byHorizon Analytical; lot DPS-7058391; UPLC and mass spectrometry
StorageNot stated on the current lot CoA. Obtain and follow the supplier-issued SDS before handling or storage.
Lab recordsCurrent lot CoA (PDF) · Request supplier-issued SDS

SDS status: not currently posted. Request and review the supplier SDS before handling or storage; this page and CoA do not replace it.

Made for research

For in-vitro lab research, method development, and identity testing by qualified research customers.

Proof by lot

The available CoA is tied to this material and lot. Open it above or visit the CoA library.

Clear limits

For laboratory research only. Never for use in people or animals.

Before you order

By ordering, you confirm qualified research-only use.